Preparation of Microwave assisted of β-enaminone Derived from Bisdemethoxycurcumin

Abstract

β-enaminone was prepared by microwave assisted reaction between bisdemethoxycurcumin and ammonium acetate in presence of Montmorillonite (K-10) as catalyst. Reaction time did not exceed 60 s. The structure of product was established by 1H NMR, the spectrum is characterized by a singlet of one proton integral at 5.44 ppm which is assigned to the vinylic proton. The spectrum of 13CNMR is characterized by signal at 186.3 ppm which indicate the presence of carbonyl group. While IR spectrum characterized by strong band at 3419 cm-1 is attributed to the intermolecular hydrogen bonded phenolic group. Computational calculations using Semi-empirical method with PM3.