Measuring level luteinizing hormone (LH) and Follicle stimulating hormone (FSH) in the pituitary gland and testosterone hormone in the testes of male rats treated with thymoquinone

Abstract

The present study assess the level luteinizing hormone (LH) and Follicle stimulating hormone FSH in the pituitary gland and testosterone hormone in the testes of male rats treated with thymoquinone. Fourty eight Waster albino mature male rats Rattus norvegicus were 60 days old were randomly divided into two groups equal , each group 24 rat and in turn divided into subgroups by 8 rat for each group according to the length of time for the experiment, which lasted six weeks (every two weeks are sacrificing a group of animals ), the first group of control represented where they were to follow administration animals given a control group and one ml of physiological saline solution per day, while the rest of the animal groups and given one ml of thymoquinone a concentration of 50 mg / kg of body weight. The end of every two weeks is the sacrifice of a group of animals. The Pituitary gland and testes also weighed for the purpose of knowledge of Members mentioned weights. The results showed a significant increase (P <0.05) in weights of rats treated compared with the control group as well as a significant increase in the pituitary weights and testes concluded that thymoquinone have potent role in elevation of follicles stimulating hormone, luteinizing hormone, Testosterone hormone related to reproduction and fertility.